Thomas Thompson may refer to:
- Tommy Thompson, former United States Secretary of Health and Human Services
- Tommy Thompson (football player), an American football player in the NFL
- Tommy Thompson (footballer born 1928), former England and Aston Villa footballer
- Tommy Thompson (footballer born 1938), former Blackpool and York City footballer
- Tom Thompson (footballer born 1894), another English footballer
- Thomas Thompson (New Zealand) (1832–1919), a New Zealand politician
- Sir Thomas Thompson, 1st Baronet (1766-1828), Royal Navy admiral
- Thomas Gordon Thompson (1888–1961), American chemist and oceanographer
- Thomas Larkin Thompson (1838–1898), United States Representative from California, ambassador to Brazil
- Thomas L. Thompson (born 1939), American biblical scholar
- Thomas Perronet Thompson (1783–1869), British mathematician and author.
- Thomas W. Thompson (1766–1821), former United States Representative (1805–1807) and Senator (1814–1817) from New Hampshire, former New Hampshire State Legislator
- Thomas Thompson (American author)
- Tommy Thompson (pitcher) (1889-1963), American baseball player
- Tommy Thompson (outfielder) (1910-1971), American baseball player
- Thomas Thompson (Toronto) (1803–1868), a Toronto schoolmaster and merchant [1]
- Tommy Thompson (murderer), executed in California for the murder of Ginger Fleischli in 1998
- Thomas G. Thompson, discoverer of the SS Central America
- Thomas W. Thompson (soldier) (1839–1927), an American Civil War Medal of Honor recipient [2]
- Thomas Williams Thompson (1840–1882), an American Civil War colonel
- Tommy Thompson (baseball infielder) (born 1947), American minor league baseball player and manager
- Tommy Thompson (baseball catcher) (born 1957), American minor league baseball player and manager
See also:
- C.R. 'Tommy' Thompson(1895-1966), a WWII British naval officer and Flag Lieutenant.
- Llewellyn "Tommy" E. Thompson, Jr. (1904–1972), former United States Ambassador to the Soviet Union (1957–1962, 1967–1969) and former United States Ambassador to Austria (1955–1957).
- Tom Thomson (1877–1917), a Canadian artist
- Thomas McKean Thompson McKennan (1794–1852), United States Secretary of the Interior and United States Representative from Pennsylvania
- Thomas Thomson, Scottish chemist
- Thomas Thomson (botanist), British botanist
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